Publikationen von Graciela Delgado bei pubmed

Originalarbeiten in Zeitschriften mit Peer Review

1.       Kleber ME, Wolfert RL, De Moissl GD, Grammer TB, Dietz S, Winkelmann BR, Boehm BO, Marz W. Lipoprotein associated phospholipase a2 concentration predicts total and cardiovascular mortality independently of established risk factors (the ludwigshafen risk and cardiovascular health study). Clinical laboratory. 2011;57:659-667 http://www.ncbi.nlm.nih.gov/pubmed/22029180

2.       Brandenburg VM, Kleber ME, Vervloet MG, Tomaschitz A, Pilz S, Stojakovic T, Delgado G, Grammer TB, Marx N, Marz W, Scharnagl H. Fibroblast growth factor 23 (fgf23) and mortality: The ludwigshafen risk and cardiovascular health study. Atherosclerosis. 2014;237:53-59 http://www.ncbi.nlm.nih.gov/pubmed/25200615

3.       Delgado G, Siekmeier R, Grammer TB, Boehm BO, Marz W, Kleber ME. Alterations in the coagulation system of active smokers from the ludwigshafen risk and cardiovascular health (luric) study. Advances in experimental medicine and biology. 2014 http://www.ncbi.nlm.nih.gov/pubmed/25300683

4.       Kleber ME, Siekmeier R, Delgado G, Grammer TB, Winkelmann BR, Scharnagl H, Boehm BO, Marz W. C-reactive protein and lipoprotein-associated phospholipase a in smokers and nonsmokers of the ludwigshafen risk and cardiovascular health study. Advances in experimental medicine and biology. 2015;176

(1):139-44 www.ncbi.nlm.nih.gov/pubmed/25300684

5.       Koller L, Kleber M, Goliasch G, Sulzgruber P, Scharnagl H, Silbernagel G, Grammer T, Delgado G, Tomaschitz A, Pilz S, Marz W, Niessner A. C-reactive protein predicts mortality in patients referred for coronary angiography and symptoms of heart failure with preserved ejection fraction. European journal of heart failure. 2014;16:758-766 http://www.ncbi.nlm.nih.gov/pubmed/24806206

6.       Makela KM, Traylor M, Oksala N, Kleber ME, Seppala I, Lyytikainen LP, Hernesniemi JA, Kahonen M, Bevan S, Rothwell PM, Sudlow C, Dichgans M, Wellcome Trust Case Control C, Delgado G, Grammer TB, Scharnagl H, Markus HS, Marz W, Lehtimaki T. Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events. Atherosclerosis. 2014;234:214-217 http://www.ncbi.nlm.nih.gov/pubmed/24681816

7.       Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, … , Delgado G, …, Abecasis GR, Chasman DI, Goddard ME, Visscher PM, Hirschhorn JN, Frayling TM. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature genetics. 2014 http://www.ncbi.nlm.nih.gov/pubmed/25282103

8.       Delgado G, Siekmeier R, Kramer BK, Marz W, Kleber ME. Cotinine as a marker for risk prediction in the ludwigshafen risk and cardiovascular health study. Respiratory physiology & neurobiology. 2015;209:17-22 http://www.ncbi.nlm.nih.gov/pubmed/25461625

9.       Drechsler C, Delgado G, Wanner C, Blouin K, Pilz S, Tomaschitz A, Kleber ME, Dressel A, Willmes C, Krane V, Kramer BK, Marz W, Ritz E, van Gilst WH, van der Harst P, de Boer RA. Galectin-3, renal function, and clinical outcomes: Results from the luric and 4d studies. Journal of the American Society of Nephrology : JASN. 2015 26(9):2213-21  http://www.ncbi.nlm.nih.gov/pubmed/25568176

10.   Kleber ME, Koller L, Goliasch G, Sulzgruber P, Scharnagl H, Silbernagel G, Grammer TB, Delgado G, Tomaschitz A, Pilz S, Marz W, Niessner A. Von willebrand factor improves risk prediction in addition to n-terminal pro b-type natriuretic peptide in patients referred to coronary angiography and signs and symptoms of heart failure and preserved ejection fraction. Circulation. Heart failure. 2015;8(1):25-32  http://www.ncbi.nlm.nih.gov/pubmed/25342739

11.   Delgado GE, Siekmeier R, Kramer BK, Marz W, Kleber ME. Plasma fibrinolysis parameters in smokers and non-smokers of the ludwigshafen risk and cardiovascular health (luric) study. Advances in experimental medicine and biology. 2015 http://www.ncbi.nlm.nih.gov/pubmed/25786403

12.   Kleber ME, Delgado G, Grammer TB, Silbernagel G, Huang J, Kramer BK, Ritz E, Marz W. Uric acid and cardiovascular events: A mendelian randomization study. Journal of the American Society of Nephrology : JASN. JASN. 2015;26(11):2831-8  http://www.ncbi.nlm.nih.gov/pubmed/25788527

13.   Nuesch E, Dale C, Palmer TM, White J, Keating BJ, van Iperen EP, … , Delgado G, … , Zabaneh D, Davey Smith G, Wells JC, Leon DA, Holmes MV, Casas JP. Adult height, coronary heart disease and stroke: A multi-locus mendelian randomization meta-analysis. International journal of epidemiology. 2015 http://www.ncbi.nlm.nih.gov/pubmed/25979724

14.   Interleukin 1 Genetics C. Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A mendelian randomisation analysis. The lancet. Diabetes & endocrinology. 2015;3:243-253 http://www.ncbi.nlm.nih.gov/pubmed/25726324

15.   Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, … , Delgado G, …, Barroso I, North KE, Ingelsson E, Hirschhorn JN, Loos RJ, Speliotes EK. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518:197-206 http://www.ncbi.nlm.nih.gov/pubmed/25673413

16.   Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Magi R, … , Delgado G, …, Heid IM, Loos RJ, Cupples LA, Morris AP, Lindgren CM, Mohlke KL. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015;518:187-196 http://www.ncbi.nlm.nih.gov/pubmed/25673412

17.   Delgado GE, Siekmeier R, Kramer BK, Marz W, Kleber ME. Plasma fibrinolysis parameters in smokers and non-smokers of the ludwigshafen risk and cardiovascular health (luric) study. Advances in experimental medicine and biology. 2015;858:69-77 http://www.ncbi.nlm.nih.gov/pubmed/25786403

18.   Kleber ME, Delgado G, Grammer TB, Silbernagel G, Huang J, Kramer BK, Ritz E, Marz W. Uric acid and cardiovascular events: A mendelian randomization study. Journal of the American Society of Nephrology : JASN. 2015;26(11):2831-8 http://www.ncbi.nlm.nih.gov/pubmed/25788527

19.   Zimmermann E, Angquist LH, Mirza SS, Zhao JH, Chasman DI, Fischer K, … , FTO-Mortality Collaborating Group, …  , Metspalu A, Ridker PM, Wareham NJ, Loos RJ, Tiemeier H, Sonestedt E, Sorensen TI. Is the adiposity-associated fto gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 caucasian adults. Obesity reviews : an official journal of the International Association for the Study of Obesity. 2015;16:327-340

20.   Nelson CP, Hamby SE, Saleheen D, Hopewell JC, Zeng L, Assimes TL, … , Watkins H, Schunkert H, Danesh J, Thompson JR, Samani NJ, Consortium CACD. Genetically determined height and coronary artery disease. The New England journal of medicine. 2015;372:1608-1618 http://www.ncbi.nlm.nih.gov/pubmed/25853659

21.   Nuesch E, Dale C, Palmer TM, White J, Keating BJ, van Iperen EP, … , Delgado G, … , Zabaneh D, Davey Smith G, Wells JC, Leon DA, Holmes MV, Casas JP. Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. Int J Epidemiol 2015 http://www.ncbi.nlm.nih.gov/pubmed/25979724

22.   Consortium CAD. A comprehensive 1000 genomes-based genome-wide association meta-analysis of coronary artery disease. Nature genetics. 2015;47:1121-1130 http://www.ncbi.nlm.nih.gov/pubmed/26343387

23.   Brandenburg VM, Kleber ME, Vervloet MG, Larsson TE, Tomaschitz A, Pilz S, Stojakovic T, Delgado G, Grammer TB, Marx N, Marz W, Scharnagl H. Soluble klotho and mortality: The ludwigshafen risk and cardiovascular health study. Atherosclerosis. 2015;242:483-489 http://www.ncbi.nlm.nih.gov/pubmed/26298739

24.   Huang J, Howie B, McCarthy S, Memari Y, Walter K, Min JL, Danecek P, Malerba G, Trabetti E, Zheng HF, Consortium UK, Gambaro G, Richards JB, Durbin R, Timpson NJ, Marchini J, Soranzo N. Improved imputation of low-frequency and rare variants using the uk10k haplotype reference panel. Nat Commun. 2015;6:8111 http://www.ncbi.nlm.nih.gov/pubmed/26368830

25.   Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, … , Delgado G, … , He J, Elliott P, Tai ES, van der Harst P, Kooner JS, Chambers JC. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature genetics 2015;47(11):1282-93 http://www.ncbi.nlm.nih.gov/pubmed/26390057

26.   Koller L, Kleber ME, Brandenburg VM, Goliasch G, Richter B, Sulzgruber P, Scharnagl H, Silbernagel G, Grammer TB, Delgado G, Tomaschitz A, Pilz S, Berger R, Mortl D, Hulsmann M, Pacher R, Marz W, Niessner A. Fibroblast growth factor 23 is an independent and specific predictor of mortality in patients with heart failure and reduced ejection fraction. Circulation. Heart failure. 2015;8:1059-1067 http://www.ncbi.nlm.nih.gov/pubmed/26273098

27.   Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Delgado G, … , Lindgren CM, Heid IM, North KE, Borecki IB, Kutalik Z, Loos RJ. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS genetics 2015;11(10):e1005378 http://www.ncbi.nlm.nih.gov/pubmed/26426971 

28.   de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, … , Delgado GE, … , Folsom AR, Ridker PM, O'Donnell CJ, Smith NL, Strachan DP, Dehghan A. A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Human molecular genetics 2016;25(2):358-70 http://www.ncbi.nlm.nih.gov/pubmed/26561523

29.   Kleber ME, Delgado GE, Lorkowski S, Marz W, von Schacky C. Trans-fatty acids and mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health Study. European heart journal 2016;37(13):1072-8 http://www.ncbi.nlm.nih.gov/pubmed/26396230

30.   Kilpelainen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, … , Delgado GE, … , Klein RJ, Schadt EE, Franks PW, Lindgren CM, Leibel RL, Loos RJ. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nature communications 2016;7:10494 https://www.ncbi.nlm.nih.gov/pubmed/26833098 .

31.   Seppala I, Kleber ME, Bevan S, Lyytikainen LP, Oksala N, Hernesniemi JA, Makela KM, Rothwell PM, Sudlow C, Dichgans M, Mononen N, Vlachopoulou E, Sinisalo J, Delgado GE, Laaksonen R, Koskinen T, Scharnagl H, Kahonen M, Markus HS, Marz W, Lehtimaki T. Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke. Scientific reports 2016;6:23207. http://www.ncbi.nlm.nih.gov/pubmed/26984639

32.   Kleber ME, Delgado GE, Lorkowski S, Marz W, von Schacky C. Data on gender and subgroup specific analyses of omega-3 fatty acids in the Ludwigshafen Risk and Cardiovascular Health Study. Data in brief 2016;8:1311-21

33.   Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, … , Delgado G, … , Loos RJ, Chakravarti A, Deloukas P, Morris AP, Newton-Cheh C, Munroe PB. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature genetics 2016;48(10):1171-84 https://www.ncbi.nlm.nih.gov/pubmed/27618452 

34.   Kleber ME, Delgado GE, Lorkowski S, Marz W, von Schacky C. Omega-3 fatty acids and mortality in patients referred for coronary angiography. The Ludwigshafen Risk and Cardiovascular Health Study. Atherosclerosis 2016 http://www.ncbi.nlm.nih.gov/pubmed/27397734.

35.   Hinney A, Kesselmeier M, Jall S, Volckmar AL, Focker M, Antel J, Gcan, Wtccc, Heid IM, Winkler TW, Giant, Grant SF, Egg, Guo Y, Bergen AW, Kaye W, Berrettini W, Hakonarson H, Price Foundation Collaborative G, Children's Hospital of Philadelphia/Price F, Herpertz-Dahlmann B, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Egberts KM, Adan R, Brandys M, van Elburg A, Boraska Perica V, Franklin CS, Tschop MH, Zeggini E, Bulik CM, Collier D, Scherag A, Muller TD, Hebebrand J. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Molecular psychiatry 2016 http://www.ncbi.nlm.nih.gov/pubmed/27184124.

36.   Delgado GE, Siekmeier R, Marz W, Kleber ME. Adiponectin and Mortality in Smokers and Non-Smokers of the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study. Advances in experimental medicine and biology 2016 http://www.ncbi.nlm.nih.gov/pubmed/27358181.

37.   Delgado GE, Siekmeier R, Kramer BK, Grubler M, Tomaschitz A, Marz W, Kleber ME. The Renin-Angiotensin-Aldosterone System in Smokers and Non-Smokers of the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study. Advances in experimental medicine and biology 2016 http://www.ncbi.nlm.nih.gov/pubmed/27334735.

38.   Lin H, Mueller-Nurasyid M, Smith AV, Arking DE, Barnard J, Bartz TM, Lunetta KL, … , Delgado GE, … , Rienstra M, Jukema JW, Stricker BH, Dorr M, Albert CM, Ellinor PT. Gene-gene Interaction Analyses for Atrial Fibrillation. Scientific reports 2016;6:35371 https://www.ncbi.nlm.nih.gov/pubmed/27824142

39.   Winter MP, Kleber ME, Koller L, Sulzgruber P, Scharnagl H, Delgado G, Goliasch G, Marz W, Niessner A. Prognostic significance of tPA/PAI-1 complex in patients with heart failure and preserved ejection fraction. Thrombosis and haemostasis 2016 https://www.ncbi.nlm.nih.gov/pubmed/27975104

40.   Boger CA, Gorski M, McMahon GM, Xu H, Chang YC, van der Most PJ, … , Delgado G,…,  Pattaro C, Schlessinger D, Kottgen A, Snieder H, Parsa A, Cohen DM. NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. Journal of the American Society of Nephrology : JASN 2017 https://www.ncbi.nlm.nih.gov/pubmed/28360221

41.   Delgado GE, Kleber ME, Scharnagl H, Kramer BK, Marz W, Scherberich JE. Serum Uromodulin and Mortality Risk in Patients Undergoing Coronary Angiography. Journal of the American Society of Nephrology : JASN 2017 https://www.ncbi.nlm.nih.gov/pubmed/28242751

42.   Krane V, Genser B, Kleber ME, Drechsler C, Marz W, Delgado G, Allolio B, Wanner C, Fenske W. Copeptin Associates with Cause-Specific Mortality in Patients with Impaired Renal Function: Results from the LURIC and the 4D Study. Clinical chemistry 2017 https://www.ncbi.nlm.nih.gov/pubmed/28280053

43.   Delgado GE, Kramer BK, Lorkowski S, Marz W, von Schacky C, Kleber ME. Individual omega-9 monounsaturated fatty acids and mortality-The Ludwigshafen Risk and Cardiovascular Health Study. Journal of clinical lipidology 2017;11(1):126-135 e5 https://www.ncbi.nlm.nih.gov/pubmed/28391879

44.   Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, … , Delgado G, … , Benjamin EJ, Tanaka T, Lunetta KL, Lubitz SA, Ellinor PT, Consortium AF. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature genetics 2017;49(6):946-952 https://www.ncbi.nlm.nih.gov/pubmed/28416818.

45.   Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, … , Delgado GE, … , Borecki IB, Franks PW, North KE, Cupples LA, Loos RJF, Kilpelainen TO. Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS genetics 2017;13(4):e1006528 https://www.ncbi.nlm.nih.gov/pubmed/28448500.

46.   Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, … , Delgado GE, … , Loos RJF, Kilpelainen TO, Liu CT, Borecki IB, North KE, Cupples LA. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature communications 2017;8:14977 https://www.ncbi.nlm.nih.gov/pubmed/28443625.

47.   Zewinger S, Kleber ME, Tragante V, McCubrey RO, Schmidt AF, Direk K, … , Delgado G, … , consortium G-C, Kramer BK, Scharnagl H, Fliser D, Marz W, Speer T. Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. Lancet Diabetes Endocrinol 2017;5(7):534-543 https://www.ncbi.nlm.nih.gov/pubmed/28566218.